The facts we all should know

FACT #30

Did you know the relationship between alcohol intake and cirrhosis is exponential?

Alcohol-related harm correlates with the volume and pattern of drinking, with epidemiological studies showing an exponential dose-response relationship between alcohol and liver disease. For most countries in the WHO European region, there is a strong correlation between liver-related mortality rates and population-level alcohol consumption.

Show me the science

Rehm J, Taylor B, Mohapatra S, et al. Alcohol as a risk factor for liver cirrhosis: a systematic review and meta-analysis. Drug Alcohol Rev 2010; 29: 437–45.

Ndugga N, Lightbourne TG, Javaherian K, et al. Disparities between research attention and burden in liver diseases: implications on uneven advances in pharmacological therapies in Europe and the USA. BMJ Open 2017.

Karlsen TH, Sheron N, Zelber-Sagi S, et al. The EASL–Lancet Liver Commission: protecting the next generation of Europeans against liver disease complications and premature mortality. The Lancet 2021.

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